Ethiofencarb

Ethiofencarb

SCHEMBL8382113

CCSCc1ccccc1CNC(=O)O.CCSCc1ccccc1OC(=O)NC

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
PGR P06401 1/20 0.40
GAA P10253 1/20 0.40
PTGS1 P23219 1/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ACHE P22303 1/20 0.40
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
LMNA P02545 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 4/20 0.35
HTT P42858 1/20 0.35
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethiofencarb SCHEMBL7528780 0.90 ALDH1A1 (0.46) ALDH1A1PGRGAAPTGS1MAPK1
Ethiofencarb SCHEMBL29449861 0.89 ALDH1A1 (0.49) ALDH1A1PGRGAAPTGS1MAPK1
Ethiofencarb SCHEMBL6738022 0.89 ALDH1A1 (0.49) ALDH1A1PGRGAAPTGS1MAPK1
Ethiofencarb SCHEMBL74938 0.89 ALDH1A1 (0.49) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL947219 0.84 LMNA (0.46) ALDH1A1GAAMEN1KMT2ANPC1
SCHEMBL11796469 0.82 ALDH1A1 (0.46) ALDH1A1PGRGAAPTGS1MAPK1
Ethiofencarb SCHEMBL28835316 0.77 TSHR (0.37) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL31105729 0.74 ALDH1A1 (0.57) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL9326227 0.74 ALDH1A1 (0.57) ALDH1A1PGRGAAPTGS1MAPK1
Carbaril SCHEMBL8343919 0.73 ALDH1A1 (0.70) ALDH1A1PGRGAAPTGS1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5952386-A EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-14 US disclosed
US-5922880-A CONTROLLING INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-13 US disclosed
US-5883262-A INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-16 US disclosed
US-5872137-A AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-16 US disclosed
US-5756522-A INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-05-26 US disclosed
US-5684022-A ANTIFERTILITY AGENT PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-11-04 US disclosed