Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27825801 | 0.81 | OR51E2 (0.40) | OR51E2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL3809261 | 0.81 | OR51E2 (0.40) | OR51E2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL3808120 | 0.81 | OR51E2 (0.40) | OR51E2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL4208208 | 0.77 | LMNA (0.38) | OR51E2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL4214657 | 0.76 | PDE4A (0.39) | OR51E2LMNAALDH1A1KDM4EDUSP3 | |
| Water SCHEMBL15418050 | 0.76 | OR51E2 (0.41) | OR51E2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL11403572 | 0.74 | POLB (0.33) | LMNAPGK1PGK2FNTAFNTB | |
| SCHEMBL4671980 | 0.74 | LMNA (0.36) | OR51E2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL1765970 | 0.74 | SLC22A6 (0.41) | OR51E2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL882914 | 0.74 | LMNA (0.44) | LMNAALDH1A1KDM4EDUSP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436136-B1 | Shaped bodies for use as implants in human medicine and method for the production of such shaped bodies | ARTIMPLANT AB (SE) | 2002-08-20 | — | — | US | claimed |
| EP-1027086-B1 | SHAPED BODIES FOR USE AS IMPLANTS IN HUMAN MEDICINE AND METHOD FOR THE PRODUCTION OF SUCH SHAPED BODIES | ARTIMPLANT AB (SE) | 2002-04-17 | — | — | EP | claimed |
| EP-1027086-A1 | SHAPED BODIES FOR USE AS IMPLANTS IN HUMAN MEDICINE AND METHOD FOR THE PRODUCTION OF SUCH SHAPED BODIES | Artimplant AB (SE) | 2000-08-16 | — | — | EP | claimed |
| WO-1999022780-A1 | SHAPED BODIES FOR USE AS IMPLANTS IN HUMAN MEDICINE AND METHOD FOR THE PRODUCTION OF SUCH SHAPED BODIES | ARTIMPLANT AB (SE) | 1999-05-14 | — | — | WO | claimed |
| CN-111867633-B | Covalent anesthetic-polymer conjugates for achieving prolonged local anesthesia | 儿童医学中心公司 | 2023-09-22 | — | — | CN | disclosed |
| US-20210275678-A1 | COVALENT ANESTHETIC-POLYMER CONJUGATES FOR PROLONGED LOCAL ANESTHESIA | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-09-09 | — | — | US | disclosed |
| CN-113166031-A | Process for the preparation of dialkyl carbonates and alkanediols | 国际壳牌研究有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-111867633-A | Covalent narcotic-polymer conjugates for achieving prolonged local anesthesia | 儿童医学中心公司 | 2020-10-30 | — | — | CN | disclosed |
| EP-3717017-A1 | COVALENT ANESTHETIC-POLYMER CONJUGATES FOR PROLONGED LOCAL ANESTHESIA | The Children's Medical Center Corporation (US) | 2020-10-07 | — | — | EP | disclosed |
| US-6436136-B1 | Shaped bodies for use as implants in human medicine and method for the production of such shaped bodies | ARTIMPLANT AB (SE) | 2002-08-20 | — | — | US | disclosed |
| EP-1027086-B1 | SHAPED BODIES FOR USE AS IMPLANTS IN HUMAN MEDICINE AND METHOD FOR THE PRODUCTION OF SUCH SHAPED BODIES | ARTIMPLANT AB (SE) | 2002-04-17 | — | — | EP | disclosed |
| EP-1027086-A1 | SHAPED BODIES FOR USE AS IMPLANTS IN HUMAN MEDICINE AND METHOD FOR THE PRODUCTION OF SUCH SHAPED BODIES | Artimplant AB (SE) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999022780-A1 | SHAPED BODIES FOR USE AS IMPLANTS IN HUMAN MEDICINE AND METHOD FOR THE PRODUCTION OF SUCH SHAPED BODIES | ARTIMPLANT AB (SE) | 1999-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210275678-A1 | COVALENT ANESTHETIC-POLYMER CONJUGATES FOR PROLONGED LOCAL ANESTHESIA | TNNC1, TNNT2, TNNI3 | OR51E2 450/4885LMNA 1768/4885ALDH1A1 4124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.