Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6715257 | 0.95 | MCHR1 (0.51) | MCHR1ADRA1ADRD2ADRA1DADRA1B | |
| SCHEMBL7559427 | 0.76 | ADRA1D (0.47) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL7271991 | 0.76 | CACNA1F (0.46) | — | |
| SCHEMBL9475602 | 0.75 | MAPT (0.49) | — | |
| SCHEMBL6786820 | 0.72 | ADRA1D (0.46) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL7272032 | 0.72 | ALDH1A1 (0.48) | — | |
| SCHEMBL9476292 | 0.72 | CACNA1F (0.53) | — | |
| SCHEMBL9475062 | 0.71 | ALDH1A1 (0.49) | — | |
| SCHEMBL10911256 | 0.70 | CACNA1F (0.56) | — | |
| SCHEMBL9476068 | 0.70 | CACNA1F (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246847-A2 | DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF | Synaptic Pharmaceutical Corporation (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2002002744-A2 | DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2002-01-10 | — | — | WO | disclosed |