Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18652968 | 0.79 | — | — | |
| SCHEMBL7785949 | 0.76 | HSD11B1 (0.33) | — | |
| SCHEMBL457124 | 0.75 | SIGMAR1 (0.33) | APLNR | |
| SCHEMBL1808280 | 0.71 | HSD11B1 (0.33) | — | |
| SCHEMBL7221175 | 0.71 | HSD11B1 (0.33) | — | |
| SCHEMBL1512245 | 0.67 | — | — | |
| SCHEMBL9492073 | 0.67 | — | — | |
| SCHEMBL29037442 | 0.62 | TGM2 (0.31) | APLNR | |
| SCHEMBL3078856 | 0.62 | SIGMAR1 (0.35) | — | |
| SCHEMBL295067 | 0.60 | HSD11B1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002002190-A2 | PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES BY GLUTATHIONE AND PHASE II DETOXIFICATION ENZYMES | JOHNS HOPKINS SCHOOL OF MEDICINE (US) | 2002-01-10 | — | — | WO | disclosed |
| WO-1994019948-A9 | CHEMOPROTECTIVE ISOTHIOCYANATES | — | 1994-11-10 | — | — | WO | disclosed |