Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560433 | 0.80 | ALDH1A1 (0.46) | MEN1KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL7534054 | 0.79 | ALDH1A1 (0.43) | MEN1KMT2AKDM4EALDH1A1TRPM8 | |
| SCHEMBL25695968 | 0.78 | HTR7 (0.50) | MEN1KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL27331113 | 0.75 | TP53 (0.49) | MEN1KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL25695965 | 0.74 | MAPT (0.48) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL28932929 | 0.73 | ALOX5 (0.49) | MEN1KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL29900630 | 0.73 | ALOX5 (0.49) | MEN1KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL2453170 | 0.72 | TP53 (0.49) | MEN1KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL2453168 | 0.72 | TP53 (0.49) | MEN1KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL15155861 | 0.72 | MAPT (0.48) | MEN1KMT2AALDH1A1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024192-A1 | DIPEPTIDE LIGANDS OF THE NPFF RECEPTOR FOR TREATING PAIN AND HYPERALGESIA | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2002-03-28 | — | — | WO | claimed |