Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 2/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | HNF4A | P41235 | 1/20 | 0.48 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1272896 | 0.83 | ALDH1A1 (0.55) | HMGB1MMP2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL110532 | 0.82 | ALDH1A1 (0.70) | HMGB1MMP2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8436637 | 0.82 | HNF4A (0.55) | HMGB1MMP2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL14645922 | 0.82 | ALOX5 (0.50) | HMGB1MMP2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7820247 | 0.81 | ALDH1A1 (0.64) | HMGB1ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL1582462 | 0.81 | HNF4A (0.63) | HMGB1MMP2ALDH1A1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL28210457 | 0.80 | ALDH1A1 (0.67) | HMGB1MMP2ALDH1A1KDM4EHSD17B10 | |
| Methane SCHEMBL28154128 | 0.80 | ALDH1A1 (0.67) | HMGB1MMP2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28094410 | 0.80 | ALDH1A1 (0.67) | HMGB1MMP2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9708883 | 0.80 | ALDH1A1 (0.52) | HMGB1MMP2ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103260629-A | Composition for treating and preventing diseases related to inflammatory reaction | AIHOL CORP | 2013-08-21 | — | — | CN | disclosed |
| EP-1192129-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000061549-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2000-10-19 | — | — | WO | disclosed |
| EP-0732322-B1 | Acetylsalicylic acid derivatives having a vinyl group | UBE INDUSTRIES (JP) | 1999-12-22 | — | — | EP | disclosed |
| US-5693320-A | ANTICOAGULANTS, BIOCOMPATIBILITY, MEDICAL EQUIPMENT | UBE INDUSTRIES, LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0732322-A1 | Acetylsalicylic acid derivatives having a vinyl group | UBE INDUSTRIES, LTD. (JP) | 1996-09-18 | — | — | EP | disclosed |