SCHEMBL753004

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL753003	1.00	ALDH1A1 (0.39)	ALDH1A1MEN1KMT2ACA12CA1
	SCHEMBL4673029	0.86	ALDH1A1 (0.38)	ALDH1A1MEN1KMT2ACA12CA1
	SCHEMBL4673033	0.86	ALDH1A1 (0.38)	ALDH1A1MEN1KMT2ACA12CA1
	SCHEMBL4677119	0.79	LTB4R (0.45)	ALDH1A1MEN1KMT2ALTA4HHTT
	SCHEMBL4677114	0.79	LTB4R (0.45)	ALDH1A1MEN1KMT2ALTA4HHTT
	SCHEMBL17922046	0.77	CA12 (0.39)	ALDH1A1KMT2ACA12CA1CA2
	SCHEMBL753000	0.76	CA12 (0.38)	ALDH1A1KMT2ACA12CA1CA2
	SCHEMBL16921549	0.76	CA12 (0.38)	ALDH1A1KMT2ACA12CA1CA2
	SCHEMBL4677723	0.76	ALDH1A1 (0.38)	ALDH1A1MEN1KMT2AHTTMAPT
	SCHEMBL4677725	0.76	ALDH1A1 (0.38)	ALDH1A1MEN1KMT2AHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.