Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | BRD2 | P25440 | 1/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.46 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12951910 | 0.86 | AKR1B1 (0.50) | ADRA1DALDH1A1KDM4EHDAC8HDAC6 | |
| SCHEMBL27545918 | 0.83 | HDAC8 (0.50) | ADRA1DALDH1A1KDM4EHDAC8HDAC6 | |
| SCHEMBL14817322 | 0.77 | KDM4E (0.71) | ADRA1DALDH1A1KDM4EHDAC8HDAC6 | |
| SCHEMBL1244069 | 0.77 | HDAC8 (0.53) | ADRA1DALDH1A1KDM4EHDAC8HDAC6 | |
| SCHEMBL9267101 | 0.76 | CYP11B1 (0.58) | PLA2G2AALDH1A1 | |
| SCHEMBL27700003 | 0.74 | ALDH1A1 (0.50) | ADRA1DALDH1A1KDM4EHDAC8HDAC6 | |
| SCHEMBL27944822 | 0.74 | ALDH1A1 (0.50) | ADRA1DALDH1A1KDM4EHDAC8HDAC6 | |
| SCHEMBL11241235 | 0.73 | NPC1 (0.41) | ALDH1A1KDM4EPOLBLMNAMAPT | |
| SCHEMBL3195611 | 0.73 | HDAC8 (0.49) | ADRA1DALDH1A1KDM4EHDAC8HDAC6 | |
| SCHEMBL8217059 | 0.73 | HDAC8 (0.49) | ADRA1DALDH1A1KDM4EHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400440-B1 | Amino acid derivative anticonvulsant | RES CORP TECHNOLOGIES INC (US) | 2002-03-13 | — | — | EP | disclosed |
| EP-0263506-B1 | ANTICONVULSANT COMPOSITION CONTAINING AMINO ACID DERIVATIVE AND USE OF SAID AMINO ACID DERIVATIVE | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-08-04 | — | — | EP | disclosed |
| EP-0400440-A1 | Amino acid derivative anticonvulsant | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0263506-A2 | Anticonvulsant composition containing amino acid derivative and use of said amino acid derivative | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1988-04-13 | — | — | EP | disclosed |