Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963893 | 0.85 | PTGS1 (0.43) | NPC1KMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL7675118 | 0.77 | NPC1 (0.39) | NPC1KMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL1655684 | 0.74 | ALOX5 (0.39) | NPC1KMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL7530197 | 0.73 | ADRA1D (0.55) | KMT2ARAB9AALDH1A1POLBLMNA | |
| SCHEMBL11230731 | 0.73 | NPC1 (0.41) | NPC1KMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL3363698 | 0.72 | NPC1 (0.59) | NPC1KMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL4739140 | 0.70 | KMT2A (0.45) | NPC1KMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL6217005 | 0.69 | ALDH1A1 (0.48) | NPC1KMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL30523 | 0.69 | TRIM24 (0.45) | NPC1KMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL10984099 | 0.69 | KMT2A (0.37) | NPC1KMT2ARAB9AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57144256-A | — | — | None | — | — | JP | disclosed |
| JP-S57144256-A | PREPARATION OF (1-ALKYL-5-TOLUOYL-2-PYRROLYL)ACETAMIDE DERIVATIVE | SAGAMI CHEM RES CENTER | 1982-09-06 | — | — | JP | disclosed |