Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7257548 | 0.86 | RAB9A (0.43) | GFERALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7261277 | 0.85 | TDP1 (0.42) | GFERCNR2ALDH1A1KDM4ERAB9A | |
| SCHEMBL7256831 | 0.85 | MEN1 (0.43) | GFERCNR2ALDH1A1CYP3A4KDM4E | |
| SCHEMBL7532023 | 0.81 | EGFR (0.48) | PTGS2GFERALDH1A1CYP3A4KDM4E | |
| SCHEMBL2581807 | 0.81 | CHRM1 (0.45) | PTGS2GFERPTGDR2CNR2RAB9A | |
| SCHEMBL7257598 | 0.81 | ALDH1A1 (0.39) | GFERCNR2ALDH1A1CYP3A4KDM4E | |
| SCHEMBL7257557 | 0.79 | KDM4E (0.44) | CNR2ALDH1A1CYP3A4KDM4ERAB9A | |
| SCHEMBL7262279 | 0.78 | FLT3 (0.40) | GFERCNR2ALDH1A1CYP3A4KDM4E | |
| SCHEMBL7256736 | 0.78 | CNR2 (0.40) | GFERCNR2ALDH1A1CYP3A4KDM4E | |
| SCHEMBL7256724 | 0.77 | KDM4E (0.40) | CNR2ALDH1A1CYP3A4KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202971-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING 4-QUINOLONES | LABORATOIRE L. LAFON (FR) | 2002-05-08 | — | — | EP | claimed |
| WO-2002022074-A2 | USE OF 2- AND 4- QUINOLONES FOR INHIBITING INTIMAL NEO-PROLIFERATION | LABORATOIRE L. LAFON (FR) | 2002-03-21 | — | — | WO | claimed |
| WO-2001012607-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 4-QUINOLONES FOR TREATING CANCERS | LAFON LABOR (FR) | 2001-11-22 | — | — | WO | claimed |
| WO-2001012607-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING 4-QUINOLONES FOR TREATING CANCERS | LABORATOIRE L. LAFON (FR) | 2001-02-22 | — | — | WO | claimed |
| EP-1202971-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING 4-QUINOLONES | LABORATOIRE L. LAFON (FR) | 2002-05-08 | — | — | EP | disclosed |
| WO-2002022074-A2 | USE OF 2- AND 4- QUINOLONES FOR INHIBITING INTIMAL NEO-PROLIFERATION | LABORATOIRE L. LAFON (FR) | 2002-03-21 | — | — | WO | disclosed |
| WO-2001012607-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING 4-QUINOLONES FOR TREATING CANCERS | LABORATOIRE L. LAFON (FR) | 2001-02-22 | — | — | WO | disclosed |