SCHEMBL753027

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL756376	0.86	FFAR4 (0.39)	BRD4CYP1A1CYP1A2CYP1B1RXFP1
	SCHEMBL752167	0.86	BRD4 (0.34)	BRD4MAPK14CYP1A1CYP1A2CYP1B1
	SCHEMBL752573	0.86	BRD4 (0.34)	BRD4MAPK14POLBPTGER1RXFP1
	SCHEMBL754396	0.85	BRD4 (0.41)	BRD4MAPK14POLBRECQLMEN1
	SCHEMBL754322	0.81	BRD4 (0.39)	BRD4MAPK14POLBPTGER1RXFP1
	SCHEMBL3434393	0.81	MAOB (0.38)	CYP1A1CYP1A2CYP1B1LMNAHTT
	SCHEMBL16921596	0.78	BRD4 (0.43)	BRD4MEN1KMT2ALMNAHTT
	SCHEMBL2490161	0.78	BRD4 (0.43)	BRD4PTGER1LMNAHTTKDM5A
	SCHEMBL756684	0.77	BRD4 (0.42)	BRD4MAPK14LMNAHTTKDM5A
	SCHEMBL756552	0.77	ABCG2 (0.35)	BRD4MEN1KMT2AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.