SCHEMBL756376

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL752167	0.90	BRD4 (0.34)	KDM5AKDM5BCYP1A1CYP1A2CYP1B1
	SCHEMBL754704	0.89	FFAR4 (0.37)	FFAR4KDM5AKDM5BCYP1A2BRD4
	SCHEMBL753027	0.86	BRD4 (0.36)	FFAR4KDM5AKDM5BCYP1A1CYP1A2
	SCHEMBL753747	0.82	KDM5A (0.42)	FFAR4KDM5AKDM5BCYP1A2BRD4
	SCHEMBL17922023	0.82	FFAR4 (0.39)	FFAR4KDM5AKDM5BCYP1A1CYP1A2
	SCHEMBL754396	0.82	BRD4 (0.41)	BRD4ALDH1A1SMN1; SMN2KMT2AMAPT
	SCHEMBL753782	0.81	KDM5A (0.35)	KDM5AKDM5BBRD4
	SCHEMBL754750	0.80	BRD4 (0.32)	KDM5AKDM5BCYP1A2BRD4SMN1; SMN2
	SCHEMBL16921596	0.77	BRD4 (0.43)	KDM5AKDM5BBRD4KMT2AMAOB
	SCHEMBL2490161	0.77	BRD4 (0.43)	KDM5AKDM5BBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.