SCHEMBL754396

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL756552	0.91	ABCG2 (0.35)	BRD4KMT2AMEN1ABCB1MAOA
	SCHEMBL16921596	0.86	BRD4 (0.43)	BRD4KMT2AMEN1ABCB1MAOB
	SCHEMBL2490161	0.86	BRD4 (0.43)	BRD4ABCB1LMNAHTT
	SCHEMBL756684	0.86	BRD4 (0.42)	BRD4ACHEABCB1MAPK14MAOB
	SCHEMBL753027	0.85	BRD4 (0.36)	BRD4POLBRECQLKMT2AMEN1
	SCHEMBL753747	0.85	KDM5A (0.42)	BRD4KMT2AABCB1MAOBKDM4E
	SCHEMBL751368	0.84	TP53 (0.35)	KMT2AMEN1ABCB1KDM4ETP53
	SCHEMBL755553	0.84	BRD4 (0.41)	BRD4KMT2AABCB1MAPK14MAOB
	SCHEMBL3432852	0.83	BRD4 (0.40)	BRD4POLBACHEABCB1MAOB
	SCHEMBL752167	0.82	BRD4 (0.34)	BRD4POLBRECQLKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.