Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14035613 | 0.83 | ALDH1A1 (0.53) | CYP1A2CYSLTR2CYSLTR1TSHRTDP1 | |
| SCHEMBL25412691 | 0.82 | MAPT (0.50) | CYP1A2CYSLTR2CYSLTR1TSHRTDP1 | |
| SCHEMBL31534614 | 0.82 | RAB9A (0.55) | CYP1A2CYSLTR2CYSLTR1TSHRTDP1 | |
| SCHEMBL7521060 | 0.81 | TDP1 (0.51) | CYP1A2TSHRTDP1MAPTALDH1A1 | |
| SCHEMBL7519738 | 0.80 | CHRNB2 (0.48) | CYP1A2TSHRTDP1MAPTALDH1A1 | |
| SCHEMBL12190689 | 0.79 | MAPT (0.49) | CYP1A2TSHRTDP1MAPTALDH1A1 | |
| SCHEMBL14008900 | 0.77 | CYP19A1 (0.62) | MAPTALDH1A1MEN1KMT2ACYP19A1 | |
| SCHEMBL8163799 | 0.76 | MAPT (0.66) | CYP1A2TSHRTDP1MAPTALDH1A1 | |
| SCHEMBL8159350 | 0.76 | MAPT (0.55) | CYSLTR2CYSLTR1TSHRTDP1PTGDR2 | |
| SCHEMBL27837027 | 0.76 | CYSLTR2 (0.55) | CYP1A2CYSLTR2CYSLTR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173414-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064864-A9 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RES CAMPAIGN TECH (GB) | 2001-12-27 | — | — | WO | disclosed |
| WO-2000064864-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-11-02 | — | — | WO | disclosed |