Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264550 | 0.82 | MAP3K14 (0.40) | MAP3K14GAATSHRMEN1APEX1 | |
| SCHEMBL3949247 | 0.82 | MAP3K14 (0.40) | MAP3K14GAATSHRMEN1APEX1 | |
| SCHEMBL2782193 | 0.80 | MEN1 (0.40) | MAP3K14MEN1APEX1KMT2ATDP1 | |
| SCHEMBL57232 | 0.80 | MAP3K14 (0.39) | MAP3K14GAATSHRMEN1APEX1 | |
| SCHEMBL977159 | 0.78 | MAP3K14 (0.38) | MAP3K14MEN1APEX1KMT2ATDP1 | |
| SCHEMBL18015890 | 0.78 | MAP3K14 (0.38) | MAP3K14GAATSHRMEN1APEX1 | |
| SCHEMBL11097052 | 0.78 | CYP19A1 (0.36) | MAP3K14CRBNDDB1CYP19A1LMNA | |
| SCHEMBL3805680 | 0.77 | MAP3K14 (0.36) | MAP3K14MEN1APEX1KMT2ATDP1 | |
| SCHEMBL756451 | 0.77 | CRBN (0.38) | MAP3K14GAATSHRMEN1APEX1 | |
| SCHEMBL4395652 | 0.76 | MAP3K14 (0.39) | MAP3K14MEN1APEX1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028910-A2 | GEOMETRICALLY EFFICIENT PARTICLE AGGLUTINATION, PARTICULARLY TO DETECT LOW AFFINITY BINDING | PALTI YORAM PROF (IL) | 2002-04-11 | — | — | WO | disclosed |
| EP-0904361-A1 | IMMOBILIZED ALLIINASE AND CONTINUOUS PRODUCTION OF ALLICIN | YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) | 1999-03-31 | — | — | EP | disclosed |
| WO-1997039115-A1 | IMMOBILIZED ALLIINASE AND CONTINUOUS PRODUCTION OF ALLICIN | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1997-10-23 | — | — | WO | disclosed |