Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.43 |
| ▸ | CASP6 | P55212 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014742 | 0.91 | PARP1 (0.55) | PARP1HDAC6TDP1THRBBLM | |
| SCHEMBL18216607 | 0.87 | PARP1 (0.55) | PARP1HDAC6TDP1THRBBLM | |
| SCHEMBL29534191 | 0.83 | PTPN11 (0.54) | PARP1TDP1THRBBLMMEN1 | |
| SCHEMBL3267890 | 0.83 | PTPN11 (0.54) | PARP1TDP1THRBBLMMEN1 | |
| SCHEMBL6394641 | 0.81 | PARP1 (0.61) | PARP1HDAC6TDP1THRBBLM | |
| SCHEMBL14980277 | 0.79 | ALDH1A1 (0.49) | PARP1TDP1THRBBLMMEN1 | |
| SCHEMBL9225081 | 0.79 | CDK1 (0.57) | TDP1THRBBLMMEN1KMT2A | |
| SCHEMBL9221704 | 0.77 | CDK1 (0.56) | TDP1THRBBLMMEN1KMT2A | |
| Benzene SCHEMBL28024147 | 0.77 | CDK1 (0.56) | PARP1HDAC6TDP1THRBBLM | |
| SCHEMBL6388584 | 0.76 | ADORA2B (0.53) | PARP1TDP1THRBBLMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102161743-B | Solvent-free aqueous polyurethane dispersion and preparation and application thereof | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2016-04-06 | — | — | CN | disclosed |
| CN-102161743-A | Solvent free aqueous polyurethane dispersions and methods of making and using the same | AIR PROD & CHEM | 2011-08-24 | — | — | CN | disclosed |
| US-20020055602-A1 | Aromatic polyisocyanates blocked by pyrazole or pyrazole derivatives and the preparation and use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-09 | — | — | US | disclosed |
| EP-1184400-A1 | Aromatic polyisocyanates blocked with pyrazole or pyrazole derivatives, process for their preparation and their use | BAYER AG (DE) | 2002-03-06 | — | — | EP | disclosed |
| US-6022449-A | HIGHER RETENTION BUT ALSO TO IMPROVED DRY AND WET STRENGTH AND SIZING. | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-08 | — | — | US | disclosed |
| US-5770651-A | POLYURETHANE CONTAINING BOTH CATIONIC AND ANIONIC GROUPS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-23 | — | — | US | disclosed |
| US-5607482-A | BLOCKED POLYISOCYANATE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |
| US-5342556-A | Microcapsules made of isocyanates with groups containing polyethylene oxide | BAYER AKTIENGESELLSCHAFT (DE) | 1994-08-30 | — | — | US | disclosed |
| US-5330841-A | Waterbase polyurethane lacquers | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-19 | — | — | US | disclosed |
| US-5268416-A | Containing no primary or secondary amino groups | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-07 | — | — | US | disclosed |
| US-5166232-A | CELLULOSE/PLASTIC BLENDS, A PROCESS FOR THEIR PRODUCTION AND THEIR USE | WOLFF WALSRODE AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |
| US-4968761-A | Process of fusing polyarylene sulfide with sulfonic acid salt | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| US-4895921-A | Water soluble or dispersible blocked polyisocyanates and a process for their preparation and use | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-23 | — | — | US | disclosed |
| EP-0339392-A1 | High molecular weight polyarylenesulfides and process for their preparation | BAYER AG (DE) | 1989-11-02 | — | — | EP | disclosed |
| US-4707386-A | Process for the production of sheet structures | BAYER AKTIENGESELLSCHAFT (DE) | 1987-11-17 | — | — | US | disclosed |
| US-4663377-A | Polyisocyanate preparation dispersible in water and their use as an additive for aqueous adhesives | BAYER AKTIENGESELLSCHAFT (DE) | 1987-05-05 | — | — | US | disclosed |
| US-4619966-A | Process for the production of coated substrates | BAYER AKTIENGESELLSCHAFT (DE) | 1986-10-28 | — | — | US | disclosed |
| US-4544683-A | GYPSUM-POLYURETHANE OR POLYURETHANE-POLYUREA | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-01 | — | — | US | disclosed |
| US-4284544-A | Process for the preparation of water-dispersible or water-soluble blocked polyisocyanates, the blocked polyisocyanates obtainable by this process and lacquer binders containing these blocked polyisocyanates as isocyanate component | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |