Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526349 | 0.93 | DNM1 (0.41) | CYP3A4ALDH1A1DNM1TDP1CA2 | |
| SCHEMBL7529088 | 0.91 | DNM1 (0.44) | DNM1TSHR | |
| SCHEMBL7526143 | 0.91 | ALDH1A1 (0.33) | CYP3A4ALDH1A1DNM1TDP1CA2 | |
| Ammonia Solution, Strong SCHEMBL28111996 | 0.89 | CYP3A4 (0.32) | CYP3A4ALDH1A1DNM1TDP1CA2 | |
| SCHEMBL23040666 | 0.88 | TSHR (0.39) | CYP3A4TSHRMMP9MMP8MMP14 | |
| SCHEMBL7534555 | 0.84 | ALDH1A1 (0.34) | CYP3A4ALDH1A1DNM1TDP1CA2 | |
| SCHEMBL23040696 | 0.84 | CYP3A4 (0.33) | CYP3A4TSHRMMP9MMP8MMP14 | |
| SCHEMBL23040674 | 0.83 | TSHR (0.35) | CYP3A4TSHRMMP9MMP8MMP14 | |
| SCHEMBL23040677 | 0.82 | CYP3A4 (0.33) | CYP3A4MMP9MMP8MMP14 | |
| SCHEMBL23040694 | 0.81 | CYP3A4 (0.32) | CYP3A4CA2CA1TSHRMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354911-A | From diacetals; catalyst composed of acid and amine | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-11 | — | — | US | claimed |
| US-9988329-B1 | Transfer-hydrogenation process | EASTMAN CHEMICAL COMPANY (US) | 2018-06-05 | — | — | US | disclosed |
| EP-0993431-B1 | METHOD FOR PRODUCING ENOL ETHERS | BASF AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-6211416-B1 | REACTING ACETAL OR KETAL WITH ACETYLENE OR ALLENE IN GAS PHASE IN PRESENCE OF CATALYST SELECTED FROM ZINC- OR CADMIUM-SILICON- AND OXYGEN-CONTAINING HETEROGENEOUS CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-03 | — | — | US | disclosed |
| EP-0993431-A1 | METHOD FOR PRODUCING ENOL ETHERS | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-19 | — | — | EP | disclosed |
| EP-0703211-B1 | Process for the preparation of unsaturated ethers | DEGUSSA (DE) | 1999-11-10 | — | — | EP | disclosed |
| WO-1998058894-A1 | METHOD FOR PRODUCING ENOL ETHERS | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-30 | — | — | WO | disclosed |
| US-5576465-A | DEHYDROETHERIFICATION OF ACETALS OR KETALS BY HEATING | HUELS AKTIENGESELLSCHAFT (DE) | 1996-11-19 | — | — | US | disclosed |
| EP-0703211-A1 | Process for the preparation of unsaturated ethers | HÜLS AKTIENGESELLSCHAFT (DE) | 1996-03-27 | — | — | EP | disclosed |
| EP-0490221-B1 | Method for the production of unsaturated ethers | HOECHST AG (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5354911-A | From diacetals; catalyst composed of acid and amine | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-11 | — | — | US | disclosed |
| EP-0490221-A2 | Method for the production of unsaturated ethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-17 | — | — | EP | disclosed |