Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28181475 | 0.90 | ALDH1A1 (0.33) | ALDH1A1CA2TSHRCA1MAPK1 | |
| Tetradecylamine SCHEMBL27594554 | 0.87 | DNM1 (0.46) | ALDH1A1TDP1CYP3A4TSHRDNM1 | |
| SCHEMBL27467883 | 0.86 | — | — | |
| SCHEMBL16541773 | 0.85 | THRB (0.36) | THRBLMNA | |
| SCHEMBL7526143 | 0.84 | ALDH1A1 (0.33) | ALDH1A1TDP1CA2CYP3A4TSHR | |
| SCHEMBL7530675 | 0.84 | CYP3A4 (0.33) | ALDH1A1TDP1CA2CYP3A4TSHR | |
| SCHEMBL7526349 | 0.82 | DNM1 (0.41) | ALDH1A1TDP1CA2CYP3A4DNM1 | |
| Ammonia Solution, Strong SCHEMBL28111996 | 0.82 | CYP3A4 (0.32) | ALDH1A1TDP1CA2CYP3A4TSHR | |
| SCHEMBL11176471 | 0.82 | THRB (0.31) | THRB | |
| SCHEMBL11185988 | 0.82 | LMNA (0.31) | ALDH1A1THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354911-A | From diacetals; catalyst composed of acid and amine | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-11 | — | — | US | claimed |
| CN-107743484-A | The amphyl for the treatment of cancer | 麦地那创新药物研究中心基金会 | 2018-02-27 | — | — | CN | disclosed |
| CN-107488172-A | A kind of preparation method of Afatinib | 山东新时代药业有限公司 | 2017-12-19 | — | — | CN | disclosed |
| CN-106187904-A | 2-phenylimidazole analog derivative containing propioloyl amido and preparation method thereof and pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2016-12-07 | — | — | CN | disclosed |
| EP-0993431-B1 | METHOD FOR PRODUCING ENOL ETHERS | BASF AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-6211416-B1 | REACTING ACETAL OR KETAL WITH ACETYLENE OR ALLENE IN GAS PHASE IN PRESENCE OF CATALYST SELECTED FROM ZINC- OR CADMIUM-SILICON- AND OXYGEN-CONTAINING HETEROGENEOUS CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-03 | — | — | US | disclosed |
| EP-0993431-A1 | METHOD FOR PRODUCING ENOL ETHERS | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-19 | — | — | EP | disclosed |
| EP-0703211-B1 | Process for the preparation of unsaturated ethers | DEGUSSA (DE) | 1999-11-10 | — | — | EP | disclosed |
| US-5869418-A | COMPOSED OF A TITANIUM COMPOUND, AN ORGANOALUMINUM COCATALYST AND A FIRST AND SECOND EXTERNAL ELECTRON DONOR, WHEREIN FIRST ELECTRON DONOR IS AN ACETAL DERIVATIVE OF AN ALDEHYDE | BOREALIS HOLDING A/S (DK) | 1999-02-09 | — | — | US | disclosed |
| WO-1998058894-A1 | METHOD FOR PRODUCING ENOL ETHERS | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-30 | — | — | WO | disclosed |
| US-5576465-A | DEHYDROETHERIFICATION OF ACETALS OR KETALS BY HEATING | HUELS AKTIENGESELLSCHAFT (DE) | 1996-11-19 | — | — | US | disclosed |
| EP-0703211-A1 | Process for the preparation of unsaturated ethers | HÜLS AKTIENGESELLSCHAFT (DE) | 1996-03-27 | — | — | EP | disclosed |
| EP-0490221-B1 | Method for the production of unsaturated ethers | HOECHST AG (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5354911-A | From diacetals; catalyst composed of acid and amine | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-11 | — | — | US | disclosed |
| EP-0490221-A2 | Method for the production of unsaturated ethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-17 | — | — | EP | disclosed |
| US-4247611-A | ACETAL RESIN, ACID DONER | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-27 | — | — | US | disclosed |