Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopropane SCHEMBL8660451 | 0.94 | CYP3A4 (0.52) | CYP3A4ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL23308783 | 0.84 | LMNA (0.48) | CYP3A4ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL25964137 | 0.81 | LMNA (0.50) | CYP3A4ALDH1A1TDP1TSHRADRB2 | |
| SCHEMBL80432 | 0.80 | CYP3A4 (0.67) | CYP3A4ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL5198521 | 0.80 | CYP3A4 (0.59) | CYP3A4ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL1715469 | 0.79 | — | — | |
| Barium SCHEMBL10790747 | 0.78 | CYP3A4 (0.64) | CYP3A4ALDH1A1TDP1L3MBTL1TSHR | |
| Calcium SCHEMBL10786160 | 0.78 | CYP3A4 (0.64) | CYP3A4ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL23087841 | 0.78 | CYP3A4 (0.64) | CYP3A4ALDH1A1TDP1L3MBTL1TSHR | |
| Potassium SCHEMBL18260591 | 0.78 | CYP3A4 (0.64) | CYP3A4ALDH1A1TDP1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016068341-A1 | THIONUCLEOSIDE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | 富士フイルム株式会社 | 2016-05-06 | — | — | WO | disclosed |
| CN-102378810-B | Detergent composition and cleaning method using the same | MATSUMOTO YUSHI SEIYAKU KK | 2013-07-31 | — | — | CN | disclosed |
| CN-102378810-A | Detergent composition and cleaning method using the same | MATSUMOTO YUSHI SEIYAKU KK | 2012-03-14 | — | — | CN | disclosed |
| US-6376712-B2 | REDUCTION OF THE CORRESPONDING OXIME COMPOUND | CENTRAL GLASS COMPANY, LIMITED (JP) | 2002-04-23 | — | — | US | disclosed |
| US-20020013500-A1 | Process for producing trifluoromethylbenzylamines | CENTRAL GLASS COMPANY, LIMITED (JP) | 2002-01-31 | — | — | US | disclosed |
| US-6331649-B1 | REDUCING AN OXIME BY CATALYTIC HYDROGENTATION IN SOLVENT CONTAINING AN ACID | CENTRAL GLASS COMPANY, LIMITED (JP) | 2001-12-18 | — | — | US | disclosed |
| CN-1047614-C | Aqueous functional fluid having improved resistance to micro-organisms | CINCINNATI MILACRON INC (US) | 1999-12-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013500-A1 | Process for producing trifluoromethylbenzylamines | MAOB, CYP2F1, AGL | CYP3A4 204/4885ALDH1A1 622/4885TDP1 3320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.