Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23308783 | 0.98 | LMNA (0.48) | LMNAOPRM1SPHK1ADRB2ADRB1 | |
| SCHEMBL7530776 | 0.81 | CYP3A4 (0.57) | LMNAOPRM1ADRB2ADRB1ADRB3 | |
| SCHEMBL8387794 | 0.80 | LMNA (0.54) | LMNAOPRM1ALDH1A1DNM1CYP3A4 | |
| SCHEMBL574982 | 0.80 | LMNA (0.54) | LMNAOPRM1ALDH1A1DNM1CYP3A4 | |
| SCHEMBL2188453 | 0.80 | LMNA (0.54) | LMNAOPRM1ALDH1A1DNM1CYP3A4 | |
| SCHEMBL20253212 | 0.80 | LMNA (0.54) | LMNAOPRM1ALDH1A1DNM1CYP3A4 | |
| SCHEMBL1776604 | 0.80 | LMNA (0.54) | LMNAOPRM1ALDH1A1DNM1CYP3A4 | |
| SCHEMBL18327083 | 0.80 | LMNA (0.54) | LMNAOPRM1ALDH1A1DNM1CYP3A4 | |
| SCHEMBL21641724 | 0.80 | LMNA (0.54) | LMNAOPRM1ALDH1A1DNM1CYP3A4 | |
| SCHEMBL20394323 | 0.80 | LMNA (0.54) | LMNAOPRM1ALDH1A1DNM1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144798-A1 | IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES | GENEVANT SCIENCES GMBH (CH) | 2023-08-03 | — | — | WO | disclosed |