Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775447 | 0.80 | HTR2A (0.38) | MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2949828 | 0.76 | GAA (0.51) | MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL5059654 | 0.75 | KMT2A (0.50) | MEN1KMT2AALDH1A1 | |
| SCHEMBL28166430 | 0.69 | MEN1 (0.51) | MEN1KMT2ASLC22A12GAATDP1 | |
| SCHEMBL7529372 | 0.69 | — | — | |
| SCHEMBL4775445 | 0.68 | SMN1; SMN2 (0.54) | KMT2AGAAALDH1A1CYP2C9 | |
| SCHEMBL3808068 | 0.66 | SFRP1 (0.49) | MEN1KMT2ASLC22A12ALDH1A1CYP2C9 | |
| SCHEMBL28053508 | 0.66 | CA1 (0.32) | — | |
| SCHEMBL29418255 | 0.64 | MEN1 (0.56) | MEN1KMT2ASLC22A12ALDH1A1CYP2C9 | |
| SCHEMBL302570 | 0.64 | MEN1 (0.56) | MEN1KMT2ASLC22A12ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185488-A1 | SULPHONYLAMIDES AND CARBOXAMIDES AND THEIR USE IN ASYMMETRICAL CATALYSIS | RHODIA CHIMIE (FR) | 2002-03-13 | — | — | EP | claimed |
| WO-2000076942-A1 | SULPHONYLAMIDES AND CARBOXAMIDES AND THEIR USE IN ASYMMETRICAL CATALYSIS | RHODIA CHIMIE (FR) | 2000-12-21 | — | — | WO | claimed |