SCHEMBL4775447

SCHEMBL4775447

Cc1ccccc1S(=O)(=O)C1(N)CCCCC1N

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
PKM P14618 1/20 0.36
EPHX2 P34913 1/20 0.35
ITGB1 P05556 1/20 0.33
ITGA4 P13612 1/20 0.33
ITGB7 P26010 1/20 0.33
THRB P10828 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GAA P10253 1/20 0.33
MCOLN3 Q8TDD5 1/20 0.33
CCR1 P32246 1/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7530799 0.80 MEN1 (0.41) GAAALDH1A1MEN1KMT2A
SCHEMBL2949828 0.79 GAA (0.51) HTR2AGAAMCOLN3ALDH1A1KDM4E
SCHEMBL5059654 0.79 KMT2A (0.50) EPHX2MCOLN3ALDH1A1MEN1KMT2A
SCHEMBL4775445 0.77 SMN1; SMN2 (0.54) PKMSMN1; SMN2GAAALDH1A1KMT2A
SCHEMBL27806415 0.72 PKM (0.37) HTR2AHTR2CPKMEPHX2THRB
Cyclohexylamine SCHEMBL28425039 0.70 EPHX2 (0.43) HTR2AHTR2CPKMEPHX2THRB
SCHEMBL28053508 0.69 CA1 (0.32)
SCHEMBL6233663 0.68 HDAC4 (0.41)
SCHEMBL28789485 0.67 HTR2A (0.38) HTR2AHTR2CPKMEPHX2CCR1
SCHEMBL8338879 0.66 ALDH1A1 (0.48) HTR2AHTR2CPKMEPHX2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106083943-A Glucopyranosyl derivative and preparation method and application thereof 广东东阳光药业有限公司 2016-11-09 CN claimed
CN-106083943-A Glucopyranosyl derivative and preparation method and application thereof 广东东阳光药业有限公司 2016-11-09 CN disclosed
WO-2008003774-A1 METHOD FOR PRODUCING ENANTIOPURE FLAVANONES Technische Universität Dresden (DE) 2008-01-10 WO disclosed