SCHEMBL7530869

SCHEMBL7530869

Nc1ccc2cc(S(=O)(=O)O)[c]c(S(=O)(=O)O)c2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 4/20 0.50
CASP6 P55212 4/20 0.40
NSD2 O96028 2/20 0.40
DUSP3 P51452 1/20 0.40
PTPN5 P54829 1/20 0.40
PTPN11 Q06124 1/20 0.40
ALDH1A1 P00352 6/20 0.38
HSD17B10 Q99714 3/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
RAPGEF4 Q8WZA2 1/20 0.36
TSHR P16473 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
RECQL P46063 3/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
CYP3A4 P08684 1/20 0.35
THRB P10828 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
CASP1 P29466 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2472818 0.84 NT5E (0.54) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL7585412 0.82 ALDH1A1 (0.50) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL1964395 0.78 CYP2D6 (0.44) ALDH1A1HSD17B10CYP2C9CYP2C19RAPGEF4
SCHEMBL2152539 0.74 CASP6 (0.54) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL6559611 0.70 NT5E (0.57) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL9334347 0.69 NT5E (0.56) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL7898223 0.69 TTR (0.46) NSD2DUSP3ALDH1A1HSD17B10TDP1
SCHEMBL342572 0.68 CTDSP1 (0.55) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL9066446 0.68 NT5E (0.58) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL151762 0.68 NT5E (0.73) NT5ECASP6NSD2DUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002018922-A2 HIGH-THROUGHPUT METHOD FOR DETERMINING THE ENANTIOMERIC PURITY OF CHIRAL COMPOUNDS STUDIENGESELLSCHAFT KOHLE MBH (DE) 2002-03-07 WO disclosed