Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.31 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532238 | 0.79 | SIRT1 (0.40) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL6402101 | 0.74 | ALDH1A1 (0.42) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL7247609 | 0.74 | ALDH1A1 (0.42) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL7535419 | 0.72 | PDK2 (0.50) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL7537870 | 0.72 | PDK2 (0.50) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL7539368 | 0.72 | PDK2 (0.50) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL6406585 | 0.72 | TACR1 (0.44) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL6400790 | 0.72 | TACR1 (0.44) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL6400684 | 0.72 | TACR1 (0.44) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL6401662 | 0.67 | ALDH1A1 (0.43) | ALDH1A1KDM4ETSHRTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032571-B1 | PIPERIDINYLAMINOMETHYL TRIFLUOROMETHYL CYCLIC ETHER COMPOUNDS AS SUBSTANCE P ANTAGONISTS | PFIZER (US) | 2002-06-12 | — | — | EP | claimed |