Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532277 | 1.00 | MTNR1A (0.38) | MTNR1AMTNR1BTRPV1MEN1ALDH1A1 | |
| SCHEMBL7534945 | 1.00 | MTNR1A (0.38) | MTNR1AMTNR1BTRPV1MEN1ALDH1A1 | |
| SCHEMBL7530080 | 0.93 | MTNR1A (0.39) | MTNR1AMTNR1BTRPV1MEN1ALDH1A1 | |
| SCHEMBL7533095 | 0.93 | MTNR1A (0.39) | MTNR1AMTNR1BTRPV1MEN1ALDH1A1 | |
| SCHEMBL7536742 | 0.93 | MTNR1A (0.39) | MTNR1AMTNR1BTRPV1MEN1ALDH1A1 | |
| SCHEMBL7532530 | 0.90 | BACE1 (0.36) | MTNR1AMTNR1BALDH1A1BACE1 | |
| SCHEMBL7535899 | 0.90 | MTNR1A (0.37) | MTNR1AMTNR1BPDE4D | |
| SCHEMBL7530400 | 0.87 | MTNR1A (0.36) | MTNR1AMTNR1BTRPV1MEN1ALDH1A1 | |
| SCHEMBL7531040 | 0.86 | HMGCR (0.38) | MTNR1AMTNR1BTRPV1MEN1ALDH1A1 | |
| SCHEMBL9540619 | 0.81 | ELANE (0.39) | MTNR1AMTNR1BTRPV1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585371-B1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INTERNAT H (US) | 2002-04-17 | — | — | EP | disclosed |
| US-5571506-A | AROMATIC ALDEHYDE OLIGOMERS FOR TREATMENT OF CARDIOVASCULAR DISORDERS, BONE METABOLISM, ANTILIPEMIC AGENTS AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-11-05 | — | — | US | disclosed |