Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7536742 | 0.96 | MTNR1A (0.39) | MTNR1AMTNR1BPDE4D | |
| SCHEMBL7530080 | 0.96 | MTNR1A (0.39) | MTNR1AMTNR1BPDE4D | |
| SCHEMBL7533095 | 0.96 | MTNR1A (0.39) | MTNR1AMTNR1BPDE4D | |
| SCHEMBL7530400 | 0.90 | MTNR1A (0.36) | MTNR1AMTNR1BPDE4D | |
| SCHEMBL7534945 | 0.90 | MTNR1A (0.38) | MTNR1AMTNR1BPDE4D | |
| SCHEMBL7532277 | 0.90 | MTNR1A (0.38) | MTNR1AMTNR1BPDE4D | |
| SCHEMBL7530899 | 0.90 | MTNR1A (0.38) | MTNR1AMTNR1BPDE4D | |
| SCHEMBL8959275 | 0.79 | HMGCR (0.41) | POLBPDE4DDPP4 | |
| SCHEMBL7532530 | 0.78 | BACE1 (0.36) | MTNR1AMTNR1BPOLB | |
| SCHEMBL7531040 | 0.78 | HMGCR (0.38) | MTNR1AMTNR1BPOLBPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585371-B1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INTERNAT H (US) | 2002-04-17 | — | — | EP | disclosed |
| US-5571506-A | AROMATIC ALDEHYDE OLIGOMERS FOR TREATMENT OF CARDIOVASCULAR DISORDERS, BONE METABOLISM, ANTILIPEMIC AGENTS AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-11-05 | — | — | US | disclosed |
| WO-1993000357-A1 | THERAPEUTIC POLYPEPTIDES BASED ON VON WILLEBRAND FACTOR | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1993-01-07 | — | — | WO | disclosed |