Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.65 |
| ▸ | MMP2 | P08253 | 2/20 | 0.65 |
| ▸ | MMP9 | P14780 | 2/20 | 0.65 |
| ▸ | TYR | P14679 | 2/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531081 | 1.00 | MMP1 (0.65) | MMP1MMP2MMP9TYRACHE | |
| SCHEMBL7523933 | 0.90 | TYR (0.71) | MMP1MMP2MMP9TYRACHE | |
| SCHEMBL7523925 | 0.90 | TYR (0.71) | MMP1MMP2MMP9TYRACHE | |
| SCHEMBL7523449 | 0.88 | TYR (0.65) | MMP1MMP2MMP9TYRACHE | |
| SCHEMBL7523461 | 0.88 | TYR (0.65) | MMP1MMP2MMP9TYRACHE | |
| SCHEMBL7526109 | 0.85 | TYR (0.70) | MMP9TYRACHETRPV1APP | |
| SCHEMBL7526101 | 0.85 | TYR (0.70) | MMP9TYRACHETRPV1APP | |
| SCHEMBL7521416 | 0.85 | TYR (0.79) | MMP9TYRACHETRPV1APP | |
| SCHEMBL7521409 | 0.85 | TYR (0.79) | MMP9TYRACHETRPV1APP | |
| SCHEMBL12299018 | 0.85 | TYR (0.73) | MMP9TYRACHETRPV1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900781-B1 | Phenolic acid amides of hydroxy substituted benzylamines | HAARMANN & REIMER GMBH (DE) | 2002-03-20 | — | — | EP | claimed |
| US-6117365-A | N-(3,4-DIHYDROXYBENZYL)-3,5-DIMETHOXY-4-HYDROXY-E-CINNAMIDE, FOR EXAMPLE; USE AS ANTIOXIDANTS OR AS FREE-RADICAL SCAVENGERS, IN PARTICULAR IN THE COSMETIC OR DERMATOLOGICAL FIELDS, AND IN FOODS | HAARMANN & REIMER GMBH (DE) | 2000-09-12 | — | — | US | claimed |
| US-6117365-A | N-(3,4-DIHYDROXYBENZYL)-3,5-DIMETHOXY-4-HYDROXY-E-CINNAMIDE, FOR EXAMPLE; USE AS ANTIOXIDANTS OR AS FREE-RADICAL SCAVENGERS, IN PARTICULAR IN THE COSMETIC OR DERMATOLOGICAL FIELDS, AND IN FOODS | HAARMANN & REIMER GMBH (DE) | 2000-09-12 | — | — | US | disclosed |