Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.70 |
| ▸ | ACHE | P22303 | 1/20 | 0.68 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | BACE1 | P56817 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | PTGES | O14684 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.64 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.64 |
| ▸ | KDM1A | O60341 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526109 | 1.00 | TYR (0.70) | TYRACHETRPV1CYP2D6CYP2C9 | |
| SCHEMBL7521416 | 0.90 | TYR (0.79) | TYRACHETRPV1CYP2D6CYP2C9 | |
| SCHEMBL7521409 | 0.90 | TYR (0.79) | TYRACHETRPV1CYP2D6CYP2C9 | |
| SCHEMBL1916293 | 0.90 | TYR (0.73) | TYRACHETRPV1CYP2D6CYP2C9 | |
| SCHEMBL12299018 | 0.90 | TYR (0.73) | TYRACHETRPV1CYP2D6CYP2C9 | |
| SCHEMBL14164369 | 0.88 | TYR (0.70) | TYRACHETRPV1CYP2D6CYP2C9 | |
| SCHEMBL7523933 | 0.85 | TYR (0.71) | TYRACHETRPV1CYP2D6CYP2C9 | |
| SCHEMBL7531081 | 0.85 | MMP1 (0.65) | TYRACHETRPV1APPMMP9 | |
| SCHEMBL7531089 | 0.85 | MMP1 (0.65) | TYRACHETRPV1APPMMP9 | |
| SCHEMBL7523925 | 0.85 | TYR (0.71) | TYRACHETRPV1CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900781-B1 | Phenolic acid amides of hydroxy substituted benzylamines | HAARMANN & REIMER GMBH (DE) | 2002-03-20 | — | — | EP | claimed |
| US-6117365-A | N-(3,4-DIHYDROXYBENZYL)-3,5-DIMETHOXY-4-HYDROXY-E-CINNAMIDE, FOR EXAMPLE; USE AS ANTIOXIDANTS OR AS FREE-RADICAL SCAVENGERS, IN PARTICULAR IN THE COSMETIC OR DERMATOLOGICAL FIELDS, AND IN FOODS | HAARMANN & REIMER GMBH (DE) | 2000-09-12 | — | — | US | claimed |
| US-6117365-A | N-(3,4-DIHYDROXYBENZYL)-3,5-DIMETHOXY-4-HYDROXY-E-CINNAMIDE, FOR EXAMPLE; USE AS ANTIOXIDANTS OR AS FREE-RADICAL SCAVENGERS, IN PARTICULAR IN THE COSMETIC OR DERMATOLOGICAL FIELDS, AND IN FOODS | HAARMANN & REIMER GMBH (DE) | 2000-09-12 | — | — | US | disclosed |