Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 16/20 | 0.55 |
| ▸ | CTSS | P25774 | 16/20 | 0.55 |
| ▸ | CTSL | P07711 | 15/20 | 0.55 |
| ▸ | CTSK | P43235 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528310 | 0.98 | CTSB (0.55) | CTSBCTSSCTSLCTSKL3MBTL1 | |
| SCHEMBL7535431 | 0.93 | CTSB (0.53) | CTSBCTSSCTSLCTSK | |
| Trifluoroacetic Acid SCHEMBL7528381 | 0.90 | CTSB (0.50) | CTSBCTSSCTSLCTSK | |
| SCHEMBL7529882 | 0.84 | CTSB (0.57) | CTSBCTSSCTSLCTSK | |
| SCHEMBL7533780 | 0.84 | CTSB (0.57) | CTSBCTSSCTSLCTSK | |
| SCHEMBL7532628 | 0.82 | CTSB (0.58) | CTSBCTSSCTSLCTSK | |
| SCHEMBL7531252 | 0.82 | CTSB (0.63) | CTSBCTSSCTSLCTSK | |
| SCHEMBL7532248 | 0.81 | CTSL (0.47) | CTSBCTSSCTSLCTSK | |
| SCHEMBL7528316 | 0.81 | CTSB (0.62) | CTSBCTSSCTSLCTSK | |
| SCHEMBL7531161 | 0.80 | CTSL (0.47) | CTSBCTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | claimed |
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |