Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 15/20 | 0.57 |
| ▸ | CTSS | P25774 | 15/20 | 0.57 |
| ▸ | CTSL | P07711 | 14/20 | 0.57 |
| ▸ | CTSK | P43235 | 4/20 | 0.44 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531250 | 0.84 | CTSB (0.55) | CTSBCTSSCTSLCTSK | |
| SCHEMBL7532248 | 0.84 | CTSL (0.47) | CTSBCTSSCTSLCTSKTACR2 | |
| SCHEMBL7533893 | 0.83 | CTSB (0.60) | CTSBCTSSCTSLCTSKTACR2 | |
| SCHEMBL7528310 | 0.83 | CTSB (0.55) | CTSBCTSSCTSLCTSK | |
| SCHEMBL7529887 | 0.81 | CTSB (0.64) | CTSBCTSSCTSLCTSKTACR2 | |
| SCHEMBL7535944 | 0.79 | MAPT (0.42) | CTSBCTSSCTSLCTSKMAPT | |
| SCHEMBL7531423 | 0.79 | CTSL (0.39) | CTSBCTSSCTSLCTSKTACR2 | |
| SCHEMBL7533002 | 0.79 | FAAH (0.38) | CTSSCTSLCTSKKMT2A | |
| SCHEMBL7535316 | 0.78 | CTSL (0.40) | CTSBCTSSCTSLCTSK | |
| SCHEMBL7535431 | 0.78 | CTSB (0.53) | CTSBCTSSCTSLCTSKLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |