SCHEMBL753159

SCHEMBL753159

COC(=O)c1ccc(N)c(C)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.62
ALDH1A1 P00352 8/20 0.62
MAPT P10636 8/20 0.62
HPGD P15428 7/20 0.62
HSD17B10 Q99714 3/20 0.62
GAA P10253 3/20 0.62
GLA P06280 1/20 0.62
CASP1 P29466 1/20 0.62
CASP7 P55210 1/20 0.62
ATM Q13315 1/20 0.62
TDP1 Q9NUW8 1/20 0.53
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA12 O43570 2/20 0.53
CA7 P43166 2/20 0.53
CA9 Q16790 2/20 0.53
CA14 Q9ULX7 2/20 0.53
XDH P47989 1/20 0.53
USP2 O75604 1/20 0.53
LMNA P02545 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8134690 0.87 SLC2A1 (0.52) KDM4EALDH1A1MAPTHPGDHSD17B10
Toluic Acid SCHEMBL15941113 0.85 ALDH1A1 (0.51) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL27501815 0.85 MAPT (0.46) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL31268024 0.85 MAPT (0.68) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL85805 0.85 MAPT (0.68) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL29375113 0.84 KDM4E (0.72) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL192100 0.84 KDM4E (0.72) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL5674062 0.83 MAPT (0.47) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL29648344 0.83 MAPT (0.61) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL27958440 0.83 MAPT (0.44) KDM4EALDH1A1MAPTHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 602 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118619922-A Hydroxamic acid compound, and preparation method and application thereof 郑州大学 2024-09-10 CN claimed
CN-116730657-B Cold patch asphalt mixture and preparation method thereof 芜湖城瑞路桥建设有限公司 2024-07-12 CN claimed
CN-116730657-A Cold patch asphalt mixture and preparation method thereof 芜湖城瑞路桥建设有限公司 2023-09-12 CN claimed
CN-109415553-B Plasticized thermoset resins and related cured resins, curing methods, and articles comprising cured resins 马萨诸塞大学 2022-08-05 CN claimed
EP-3396028-B1 DIRECT ELECTROCHEMICAL SYNTHESIS OF DOPED CONDUCTIVE POLYMERS ON METAL ALLOYS BOEING CO (US) 2022-04-06 EP claimed
CN-109761817-B Synthetic method of nefiracetam intermediate 2, 6-dimethylaniline 深圳市第二人民医院 2021-11-16 CN claimed
CN-109761817-A The synthetic method of Nefiracetam intermediate 2,6- dimethylaniline 深圳市第二人民医院 2019-05-17 CN claimed
EP-3481899-A1 PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN The University of Massachusetts (US) 2019-05-15 EP claimed
CN-109415553-A The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin 马萨诸塞大学 2019-03-01 CN claimed
WO-2018008003-A1 PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN THE UNIVERSITY OF MASSACHUSETTS (US) 2018-01-11 WO claimed
US-7211202-B2 Process to make a conductive composition of a fluorinated polymer which contains polyaniline ATOFINA (FR) 2007-05-01 US claimed
EP-1428857-B1 Process to make a conductive composition of a fluorinated polymer which contains polyaniline ARKEMA FRANCE (FR) 2007-01-31 EP claimed
US-5415893-A Dispersion of electrically conductive particles in a dispersing medium DSM N.V. (NL) 1995-05-16 US claimed
JP-7126367-A None JP disclosed
CN-122036615-A Indazole hydrazide compound and preparation method and application thereof 南京农业大学 2026-05-15 CN disclosed
US-12479836-B2 Sphingosine-1-phosphate receptor agonist, preparation method therefor, and pharmaceutical composition containing same as active ingredient LG CHEM, LTD. (KR) 2025-11-25 US disclosed
US-5262483-A Styrene-maleic anhydride and polyaniline grafted with processability and conductivity DSM N.V. (NL) 1993-11-16 US disclosed
EP-0538939-A1 Polymer composition DSM N.V. (NL) 1993-04-28 EP disclosed
EP-0035393-A1 Poultry feeds containing and methods of using anovulatory compounds, and novel anovulatory imidazolines MERCK & CO. INC. (US) 1981-09-09 EP disclosed
US-4287201-A CONTAINING A 2-(SUBSTITUTED PHENYLIMINO)IMIDAZOLIDINE COMPOUND MERCK & CO., INC. (US) 1981-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479836-B2 Sphingosine-1-phosphate receptor agonist, preparation method therefor, and pharmaceutical composition containing same as active ingredient S1PR1, S1PR2, S1PR4 KDM4E 3159/4885ALDH1A1 2529/4885MAPT 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.