SCHEMBL85805

SCHEMBL85805

COC(=O)c1ccc(C)c(N)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.68
KDM4E B2RXH2 9/20 0.68
ALDH1A1 P00352 9/20 0.68
HPGD P15428 7/20 0.68
HSD17B10 Q99714 4/20 0.68
GAA P10253 4/20 0.68
GLA P06280 1/20 0.68
CASP1 P29466 1/20 0.68
CASP7 P55210 1/20 0.68
ATM Q13315 1/20 0.68
TDP1 Q9NUW8 2/20 0.66
USP2 O75604 1/20 0.57
LMNA P02545 3/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
MAPK1 P28482 2/20 0.56
ALOX15 P16050 2/20 0.56
NPC1 O15118 3/20 0.54
NPSR1 Q6W5P4 2/20 0.54
RAB9A P51151 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31268024 1.00 MAPT (0.68) MAPTKDM4EALDH1A1HPGDHSD17B10
Hydrochloric Acid SCHEMBL6982886 0.98 MAPT (0.66) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL11143238 0.89 MAPT (0.55) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL11136958 0.85 PRSS1 (0.60) MAPTKDM4EALDH1A1HPGDHSD17B10
Toluic Acid SCHEMBL15941077 0.85 ALDH1A1 (0.55) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL753159 0.85 KDM4E (0.62) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL192100 0.84 KDM4E (0.72) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL29375113 0.84 KDM4E (0.72) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL28088268 0.84 MAPT (0.59) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL27989804 0.83 MAPT (0.63) MAPTKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 918 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730657-B Cold patch asphalt mixture and preparation method thereof 芜湖城瑞路桥建设有限公司 2024-07-12 CN claimed
CN-113419004-B Method for detecting impurities in methyl 3-amino-4-methylbenzoate 海南鑫开源医药科技有限公司 2023-04-18 CN claimed
CN-113419004-A Method for detecting impurities in methyl 3-amino-4-methylbenzoate 海南鑫开源医药科技有限公司 2021-09-21 CN claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-12630497-B2 Compound having malate dehydrogenase inhibitory activity and pharmaceutical composition for preventing or treating cancer comprising same as active ingredient DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2026-05-19 US disclosed
EP-3856179-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-05-13 EP disclosed
EP-4739682-A1 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS Janssen Pharmaceutica NV (BE) 2026-05-13 EP disclosed
US-20260125400-A1 TYK2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-05-07 US disclosed
EP-4722212-A1 NOVEL COMPOUND FOR INHIBITING PROTEIN KINASES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Magicbullettherapeutics Co., Ltd. (KR) 2026-04-08 EP disclosed
US-12577243-B2 Monoacylglycerol lipase modulators JANSSEN PHARMACEUTICA NV (BE) 2026-03-17 US disclosed
EP-3856178-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-03-11 EP disclosed
US-12551490-B2 Heterocyclic modulators of lipid synthesis SAGIMET BIOSCIENCES INC. (US) 2026-02-17 US disclosed
US-4421601-A LACQUERS, INKS, PAINTS, TEXTILES, PAPER BAYER AKTIENGESELLSCHAFT (DE) 1983-12-20 US disclosed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US disclosed
US-4260540-A SPIN DYEING POLYACRYLONITRILE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed
US-4246401-A Axomethine pigments BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
US-4139530-A CATIONIC DYES BAYER AKTIENGESELLSCHAFT (DE) 1979-02-13 US disclosed
US-4070353-A FOR PLASTICS AND PRINTING INKS, YELLOW TO ORANGE SHADES CIBA-GEIGY CORPORATION (US) 1978-01-24 US disclosed
US-4014863-A LACQUERS, PRINTING INKS, PAINTS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125400-A1 TYK2 DEGRADERS AND USES THEREOF TYK2, CSNK2A1, CSNK2A2 MAPT 4245/4885KDM4E 810/4885ALDH1A1 3930/4885
US-12630497-B2 Compound having malate dehydrogenase inhibitory activity and pharmaceutical composition for preventing or treating cancer comprising same as active ingredient MDH2, MDH1, ME2 MAPT 3599/4885KDM4E 820/4885ALDH1A1 192/4885
US-12577243-B2 Monoacylglycerol lipase modulators MGLL, LPL, FAAH MAPT 3782/4885KDM4E 3565/4885ALDH1A1 587/4885
US-12551490-B2 Heterocyclic modulators of lipid synthesis FASN, FADS1, FADS2 MAPT 4749/4885KDM4E 1054/4885ALDH1A1 540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.