Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053418 | 0.89 | CCR3 (0.65) | GRIN2B | |
| SCHEMBL9050713 | 0.84 | CCR3 (0.66) | — | |
| SCHEMBL12123850 | 0.84 | ACHE (0.78) | GRIN2B | |
| Hydrochloric Acid SCHEMBL9053162 | 0.83 | CCR3 (0.65) | — | |
| SCHEMBL5969423 | 0.82 | CCR3 (0.67) | — | |
| SCHEMBL4499983 | 0.81 | CYP2J2 (0.65) | — | |
| SCHEMBL4512783 | 0.81 | DRD2 (0.71) | — | |
| SCHEMBL4832269 | 0.81 | GRIN2B (0.60) | GRIN2B | |
| Hydrochloric Acid SCHEMBL7303580 | 0.81 | DRD2 (0.69) | — | |
| Bromide SCHEMBL7383167 | 0.80 | SIGMAR1 (0.50) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002030422-A1 | USE OF DEFINED SUBSTANCES THAT BIND TO THE SIGMA RECEPTOR FOR COMBATING SARCOMA AND CARCINOMA | MERCK PATENT GMBH (DE) | 2002-04-18 | — | — | WO | claimed |
| WO-2002030422-A1 | USE OF DEFINED SUBSTANCES THAT BIND TO THE SIGMA RECEPTOR FOR COMBATING SARCOMA AND CARCINOMA | MERCK PATENT GMBH (DE) | 2002-04-18 | — | — | WO | disclosed |
| WO-2002030422-A1 | USE OF DEFINED SUBSTANCES THAT BIND TO THE SIGMA RECEPTOR FOR COMBATING SARCOMA AND CARCINOMA | MERCK PATENT GMBH (DE) | 2002-04-18 | — | — | WO | disclosed |