Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680432 | 0.88 | PPARG (0.41) | PPOXDHODH | |
| SCHEMBL6794821 | 0.87 | PPOX (0.44) | PPOXKMT2ANPBWR1MCHR1GAA | |
| SCHEMBL4681493 | 0.87 | PPOX (0.43) | PPOXKMT2AGAAATMDHODH | |
| SCHEMBL4681826 | 0.86 | DHODH (0.34) | PPOXKMT2AMEN1NR1I2TDP1 | |
| SCHEMBL4681716 | 0.85 | PPOX (0.55) | PPOXKMT2AMEN1GAAATM | |
| SCHEMBL27520995 | 0.82 | GAA (0.37) | KMT2ANR1I2TDP1NPBWR1MCHR1 | |
| SCHEMBL31442437 | 0.81 | PPOX (0.44) | PPOXKMT2AMEN1NR1I2TDP1 | |
| SCHEMBL4679803 | 0.81 | PPOX (0.44) | PPOXKMT2AMEN1NR1I2TDP1 | |
| SCHEMBL8153591 | 0.80 | GAA (0.36) | KMT2AMEN1NPBWR1MCHR1GAA | |
| SCHEMBL10460255 | 0.79 | PPOX (0.46) | PPOXKMT2AMEN1NR1I2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934254-B1 | PRODUCTION OF PYRIDAZINE HERBICIDES | SUMITOMO CHEMICAL CO (JP) | 2002-04-17 | — | — | EP | disclosed |
| US-6333413-B1 | PYRIDAZIN-3-ONE DERIVATIVES BY CYCLIZING THE CARBOXY-SUBSTITUTED HYDRAZONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-12-25 | — | — | US | disclosed |
| US-6156891-A | Production of pyridazine herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0934254-A1 | PRODUCTION OF PYRIDAZINE HERBICIDES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017632-A1 | PRODUCTION OF PYRIDAZINE HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-30 | — | — | WO | disclosed |