Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.41 |
| ▸ | PPOX | P50336 | 4/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4681493 | 0.90 | PPOX (0.43) | PPOXKDM4EALDH1A1DHODH | |
| SCHEMBL4681716 | 0.88 | PPOX (0.55) | PPOXALDH1A1HPGDDHODH | |
| SCHEMBL7532202 | 0.88 | PPOX (0.44) | PPOXDHODH | |
| SCHEMBL6794821 | 0.82 | PPOX (0.44) | PPOXALDH1A1DHODH | |
| SCHEMBL4682523 | 0.82 | PPOX (0.41) | PPARGPPOXPTGDR2KDM4EALDH1A1 | |
| SCHEMBL10458512 | 0.81 | PPOX (0.41) | PPOXKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4682095 | 0.80 | PKM (0.34) | KDM4EALDH1A1 | |
| SCHEMBL4682067 | 0.80 | SMN1; SMN2 (0.35) | KDM4EALDH1A1DHODH | |
| SCHEMBL4062616 | 0.78 | SORT1 (0.37) | HPGD | |
| SCHEMBL31448207 | 0.78 | SORT1 (0.37) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850227-B1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2008-01-09 | — | — | EP | claimed |