Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935713 | 0.91 | NPBWR1 (0.34) | GAAATMALOX5APFEN1L3MBTL1 | |
| SCHEMBL7935810 | 0.88 | KMT2A (0.39) | GAAATML3MBTL1NPBWR1ALDH1A1 | |
| SCHEMBL6794821 | 0.83 | PPOX (0.44) | GAAATML3MBTL1NPBWR1ALDH1A1 | |
| SCHEMBL7926378 | 0.83 | ALDH1A1 (0.43) | GAAATMALDH1A1KMT2AHPGD | |
| SCHEMBL7532202 | 0.80 | PPOX (0.44) | GAAATMNPBWR1MCHR1KMT2A | |
| SCHEMBL7926376 | 0.80 | POLB (0.46) | GAAATML3MBTL1KMT2AHPGD | |
| SCHEMBL7938605 | 0.79 | KMT2A (0.40) | GAAATML3MBTL1NPBWR1ALDH1A1 | |
| SCHEMBL7932818 | 0.78 | MAPT (0.47) | L3MBTL1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL5388413 | 0.77 | GAA (0.37) | GAAATML3MBTL1NPBWR1ALDH1A1 | |
| SCHEMBL4680432 | 0.76 | PPARG (0.41) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121201-A | HETEROARYL SUBSTITUTED HALO-PYRAZOLE SUBSTITUTED DIARYL ETHERS OR THIOETHERS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2000-09-19 | — | — | US | disclosed |