SCHEMBL7532405

SCHEMBL7532405

Cn1c(I)c(Cl)c(=O)n(C)c1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
KDM4E B2RXH2 5/20 0.40
HPGD P15428 2/20 0.40
HTT P42858 2/20 0.40
JAK2 O60674 1/20 0.40
LMNA P02545 1/20 0.40
PAX8 Q06710 1/20 0.40
ADORA2A P29274 2/20 0.38
KMT2A Q03164 4/20 0.33
GLA P06280 2/20 0.33
RXFP1 Q9HBX9 2/20 0.33
MAPT P10636 2/20 0.33
GAA P10253 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
RECQL P46063 1/20 0.32
PIK3CD O00329 1/20 0.31
POLB P06746 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
CNR1 P21554 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16121001 0.75 ADORA2A (0.35) ALDH1A1KDM4EADORA2AKMT2AGLA
SCHEMBL9769938 0.75 ALDH1A1 (0.42) ALDH1A1KDM4EHPGDHTTJAK2
SCHEMBL7939182 0.71 ALDH1A1 (0.40) ALDH1A1KDM4EHPGDHTTJAK2
SCHEMBL10724834 0.71 POLB (0.36) KDM4EADORA2AKMT2ARXFP1MAPT
SCHEMBL17242241 0.71 KMT2A (0.39) ALDH1A1KDM4EHPGDHTTJAK2
SCHEMBL13575169 0.68 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDHTTJAK2
SCHEMBL11430911 0.68 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDHTTJAK2
SCHEMBL11426291 0.67 MAPT (0.40) ALDH1A1KDM4EHPGDHTTJAK2
SCHEMBL18784410 0.64 HPGD (0.34) ALDH1A1KDM4EHPGDHTTJAK2
SCHEMBL1689679 0.63 LGMN (0.36) ALDH1A1KDM4EHPGDHTTJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0737329-B1 TABULAR GRAIN EMULSIONS WITH SELECTED SITE HALIDE CONVERSIONS AND PROCESSES FOR THEIR PREPARATION EASTMAN KODAK CO (US) 2002-04-03 EP disclosed