SCHEMBL9769938

SCHEMBL9769938

Cn1c(Cl)c(Cl)c(=O)n(C)c1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
KDM4E B2RXH2 5/20 0.42
HPGD P15428 2/20 0.42
HTT P42858 2/20 0.42
JAK2 O60674 1/20 0.42
LMNA P02545 1/20 0.42
PAX8 Q06710 1/20 0.42
KMT2A Q03164 3/20 0.41
ADORA2A P29274 2/20 0.40
MAPT P10636 2/20 0.35
GLA P06280 2/20 0.35
GAA P10253 1/20 0.35
MEN1 O00255 1/20 0.33
PIK3CD O00329 1/20 0.33
POLB P06746 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
CNR1 P21554 1/20 0.33
ACHE P22303 1/20 0.33
ADORA2B P29275 1/20 0.33
ADORA1 P30542 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7793957 0.77 KMT2A (0.43) ALDH1A1KDM4EHPGDHTTJAK2
SCHEMBL7532405 0.75 ALDH1A1 (0.40) ALDH1A1KDM4EHPGDHTTJAK2
SCHEMBL17242241 0.75 KMT2A (0.39) ALDH1A1KDM4EHPGDHTTJAK2
SCHEMBL20045954 0.72 KMT2A (0.39) ALDH1A1KDM4EHPGDHTTJAK2
SCHEMBL7802796 0.72 KMT2A (0.40) ALDH1A1KDM4EHPGDHTTJAK2
SCHEMBL11430911 0.72 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDHTTJAK2
SCHEMBL474385 0.72 KMT2A (0.49) ALDH1A1KDM4EHPGDHTTJAK2
SCHEMBL23635607 0.70 HTT (0.37) ALDH1A1KDM4EHPGDHTTJAK2
SCHEMBL479900 0.70 KDM4E (0.51) ALDH1A1KDM4EHPGDHTTJAK2
SCHEMBL11426291 0.70 MAPT (0.40) ALDH1A1KDM4EHPGDHTTJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023150592-A2 N3-SUBSTITUTED URACIL COMPOUNDS AS TRPA1 INHIBITORS D.E. SHAW RESEARCH, LLC (US) 2023-08-10 WO disclosed
US-5066573-A Sulfur containing compound which functions as a bleach accereration agent FUJI PHOTO FILM CO., LTD. (JP) 1991-11-19 US disclosed
US-4966835-A HAVING A BLOCKED BLEACH ACCELERATOR CLEAVABLE DURING PROCESSING TO ALLOW FOR RAPID BLEACHING AND DESILVERING FUJI PHOTO FILM CO., LTD. (JP) 1990-10-30 US disclosed