SCHEMBL753246

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10134383	0.84	MEN1 (0.83)	MEN1KMT2AKDM4EALDH1A1NPC1
	SCHEMBL4797268	0.81	MEN1 (0.59)	MEN1KMT2AKDM4EALDH1A1L3MBTL1
	SCHEMBL851116	0.81	MEN1 (0.59)	MEN1KMT2AKDM4EALDH1A1NPC1
	SCHEMBL4797272	0.81	MEN1 (0.59)	MEN1KMT2AKDM4EALDH1A1NPC1
	SCHEMBL4050755	0.80	MEN1 (0.53)	MEN1KMT2AL3MBTL1NPC1RAB9A
	SCHEMBL753331	0.80	BCAT2 (0.60)	MEN1KMT2AALDH1A1L3MBTL1NPC1
	SCHEMBL13750597	0.79	SYK (0.46)	MEN1KMT2AKDM4EALDH1A1NPC1
	SCHEMBL20176871	0.78	MEN1 (0.55)	MEN1KMT2AKDM4EALDH1A1L3MBTL1
	SCHEMBL8736571	0.78	MEN1 (0.55)	MEN1KMT2AALDH1A1NPC1RAB9A
	SCHEMBL31132915	0.77	MEN1 (0.48)	MEN1KMT2AKDM4EALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.