Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.58 |
| ▸ | HNF4A | P41235 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 2/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532470 | 1.00 | PTPN1 (0.58) | PTPN1HNF4AKDM4EHSD17B10PTPN6 | |
| SCHEMBL7529691 | 0.90 | KDM4E (0.55) | PTPN1HNF4AKDM4EHSD17B10PTPN6 | |
| SCHEMBL7529680 | 0.90 | KDM4E (0.55) | PTPN1HNF4AKDM4EHSD17B10PTPN6 | |
| SCHEMBL7524215 | 0.87 | PTGS2 (0.52) | PTPN1HNF4AKDM4EHSD17B10MAPT | |
| SCHEMBL7524206 | 0.87 | PTGS2 (0.52) | PTPN1HNF4AKDM4EHSD17B10MAPT | |
| SCHEMBL4604659 | 0.84 | ADORA3 (0.54) | PTPN1HNF4AKDM4EPTPN6PTPN2 | |
| SCHEMBL4604654 | 0.84 | ADORA3 (0.54) | PTPN1HNF4AKDM4EPTPN6PTPN2 | |
| SCHEMBL6674346 | 0.84 | MEN1 (0.62) | PTPN1HNF4AMAPTTTRMEN1 | |
| SCHEMBL6673496 | 0.84 | MEN1 (0.62) | PTPN1HNF4AMAPTTTRMEN1 | |
| SCHEMBL21428871 | 0.83 | MAPT (0.56) | PTPN1HNF4AKDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | TELIK, INC. | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | SLC2A1, SLC2A8, SLC2A2 | PTPN1 1380/4885HNF4A 425/4885KDM4E 3079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.