Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3077884 | 0.79 | ALDH1A1 (0.50) | TSHRCASP1PDE10AALDH1A1MAPT | |
| SCHEMBL7873560 | 0.79 | KDM4E (0.50) | TSHRCASP1PDE10AALDH1A1MAPT | |
| SCHEMBL30561864 | 0.79 | CYP3A4 (0.55) | TSHRCASP1ALDH1A1MAPTKDM4E | |
| SCHEMBL841555 | 0.79 | CYP3A4 (0.55) | TSHRCASP1ALDH1A1MAPTKDM4E | |
| SCHEMBL2589677 | 0.77 | KDM4E (0.55) | TSHRCASP1PDE10AALDH1A1MAPT | |
| SCHEMBL12658291 | 0.77 | KDM4E (0.48) | TSHRCASP1PDE10AALDH1A1MAPT | |
| SCHEMBL29673743 | 0.77 | CYP3A4 (0.60) | TSHRCASP1PDE10AALDH1A1MAPT | |
| SCHEMBL7525100 | 0.77 | CA1 (0.37) | TSHRALDH1A1MAPTKDM4EALOX15 | |
| SCHEMBL19738526 | 0.77 | CYP3A4 (0.39) | TSHRCASP1ALDH1A1MAPTKDM4E | |
| SCHEMBL15449430 | 0.77 | ALDH1A1 (0.55) | TSHRCASP1PDE10AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002003938-A1 | IODO-CONTAINING ORGANIC COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | CLAIROL INCORPORATED (US) | 2002-01-17 | — | — | WO | claimed |
| US-20140066410-A1 | INHIBITORS OF BROMODOMAINS AS MODULATORS OF GENE EXPRESSION | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2014-03-06 | — | — | US | disclosed |
| US-20140066410-A1 | INHIBITORS OF BROMODOMAINS AS MODULATORS OF GENE EXPRESSION | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2014-03-06 | — | — | US | disclosed |
| US-20140066410-A1 | INHIBITORS OF BROMODOMAINS AS MODULATORS OF GENE EXPRESSION | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2014-03-06 | — | — | US | disclosed |
| EP-2677865-A1 | INHIBITORS OF BROMODOMAINS AS MODULATORS OF GENE EXPRESSION | Icahn School of Medicine at Mount Sinai (US) | 2014-01-01 | — | — | EP | disclosed |
| WO-2012116170-A1 | INHIBITORS OF BROMODOMAINS AS MODULATORS OF GENE EXPRESSION | ZHOU MING-MING (US) | 2012-08-30 | — | — | WO | disclosed |
| WO-2002003938-A1 | IODO-CONTAINING ORGANIC COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | CLAIROL INCORPORATED (US) | 2002-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140066410-A1 | INHIBITORS OF BROMODOMAINS AS MODULATORS OF GENE EXPRESSION | NFKBIA, NFKB2, IKBKG | TSHR 3700/4885CASP1 1473/4885PDE10A 3624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.