SCHEMBL7532995

SCHEMBL7532995

CCOCn1c([Se]c2cc(C)cc(C)c2)c(C(C)C)c(=O)[nH]c1=S

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8428993 0.89 KDM4E (0.34) GAA
SCHEMBL7535244 0.89 ALDH1A1 (0.34)
SCHEMBL8430830 0.88 PNP (0.33)
SCHEMBL8429024 0.88 MPO (0.31)
SCHEMBL7533007 0.86 ALDH1A1 (0.45)
SCHEMBL8429213 0.85 ALDH1A1 (0.36) GAA
SCHEMBL7541334 0.84 GAA (0.33) GAA
SCHEMBL8430907 0.83 GAA (0.36) GAA
SCHEMBL8426980 0.79 MAPT (0.32) GAA
SCHEMBL9016475 0.79 KDM4E (0.32) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0748316-B1 PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES SUNKYONG IND LTD (KR) 2002-05-08 EP disclosed
US-5889013-A REACTING AN URACIL COMPOUND WITH N, O-BIS/TRIMETHYLSILYL/ACETAMIDE FOLLOWED BY TETRABUTYLAMMONIUM IODIDE AND CHLOROMETHYL ETHER COMPOUND AND THEN REACTING WITH ARYL SELENOL IN A BASE SUNKYONG INDUSTRIES CO., INC. (KR) 1999-03-30 US disclosed
EP-0748316-A1 PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES SUNKYONG INDUSTRIES CO., LTD. (KR) 1996-12-18 EP disclosed
WO-1995023138-A1 PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES SUNKYONG INDUSTRIES CO., LTD. (KR) 1995-08-31 WO disclosed