Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430852 | 0.90 | ALDH1A1 (0.36) | KDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7532995 | 0.89 | GAA (0.32) | GAA | |
| SCHEMBL9016475 | 0.89 | KDM4E (0.32) | KDM4EALDH1A1GAAMAPTCYP2C9 | |
| SCHEMBL8426834 | 0.88 | ALDH1A1 (0.43) | KDM4EALDH1A1GAAMAPTCYP2C9 | |
| SCHEMBL8429213 | 0.88 | ALDH1A1 (0.36) | KDM4EALDH1A1GAAMAPTCYP2C9 | |
| SCHEMBL8430921 | 0.85 | ALDH1A1 (0.34) | KDM4EALDH1A1GAALMNAHPGD | |
| SCHEMBL8429024 | 0.82 | MPO (0.31) | — | |
| SCHEMBL7533007 | 0.80 | ALDH1A1 (0.45) | KDM4EALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL8430914 | 0.79 | ALDH1A1 (0.51) | KDM4EALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL9016457 | 0.79 | UPP1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889013-A | REACTING AN URACIL COMPOUND WITH N, O-BIS/TRIMETHYLSILYL/ACETAMIDE FOLLOWED BY TETRABUTYLAMMONIUM IODIDE AND CHLOROMETHYL ETHER COMPOUND AND THEN REACTING WITH ARYL SELENOL IN A BASE | SUNKYONG INDUSTRIES CO., INC. (KR) | 1999-03-30 | — | — | US | disclosed |
| EP-0748316-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG INDUSTRIES CO., LTD. (KR) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023138-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG INDUSTRIES CO., LTD. (KR) | 1995-08-31 | — | — | WO | disclosed |