Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 8/20 | 0.50 |
| ▸ | FAAH | O00519 | 5/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530434 | 0.99 | DAGLA (0.52) | DAGLAFAAHCES1HDAC6HDAC3 | |
| SCHEMBL7531275 | 0.80 | TACR2 (0.49) | DAGLAFAAHCES1HDAC6HDAC3 | |
| SCHEMBL7533012 | 0.79 | FAAH (0.45) | DAGLAFAAHCES1HDAC6CTSS | |
| SCHEMBL27805184 | 0.78 | DAGLA (0.67) | DAGLAFAAHCES1HDAC6HDAC3 | |
| SCHEMBL7530247 | 0.78 | FAAH (0.44) | DAGLAFAAHCES1HDAC6HDAC3 | |
| SCHEMBL7533880 | 0.77 | TACR2 (0.52) | — | |
| SCHEMBL7535321 | 0.77 | FAAH (0.43) | DAGLAFAAHCES1HDAC6HDAC3 | |
| SCHEMBL7530914 | 0.77 | FAAH (0.43) | DAGLAFAAHCES1HDAC3HDAC1 | |
| SCHEMBL7536597 | 0.77 | FAAH (0.43) | DAGLAFAAHCES1CTSS | |
| SCHEMBL7535950 | 0.76 | CTSL (0.49) | DAGLAFAAHCES1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | claimed |
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |