Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 5/20 | 0.41 |
| ▸ | CTSB | P07858 | 5/20 | 0.41 |
| ▸ | CTSS | P25774 | 5/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7536597 | 0.91 | FAAH (0.43) | FAAHCES1DAGLACTSKCTSL | |
| SCHEMBL7535321 | 0.91 | FAAH (0.43) | FAAHCES1DAGLACTSKCTSL | |
| SCHEMBL7535950 | 0.88 | CTSL (0.49) | FAAHCES1DAGLACTSKCTSL | |
| SCHEMBL7530297 | 0.88 | CTSL (0.42) | FAAHCES1DAGLACTSKCTSL | |
| SCHEMBL7529866 | 0.88 | FAAH (0.43) | FAAHCES1DAGLACTSKCTSL | |
| SCHEMBL7530914 | 0.87 | FAAH (0.43) | FAAHCES1DAGLACTSBCTSS | |
| SCHEMBL7532252 | 0.86 | CTSL (0.54) | FAAHCES1DAGLACTSKCTSL | |
| SCHEMBL7530247 | 0.85 | FAAH (0.44) | FAAHCES1DAGLACTSKCTSL | |
| SCHEMBL7531275 | 0.85 | TACR2 (0.49) | FAAHCES1DAGLAHDAC6 | |
| SCHEMBL7531990 | 0.84 | ALDH1A1 (0.45) | FAAHCES1DAGLACTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |