Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530689 | 0.87 | CHRNA7 (0.36) | CHRNB2CHRNA4CYP1A2CYP2D6CHRM1 | |
| SCHEMBL11067132 | 0.66 | ALOX5 (0.40) | — | |
| SCHEMBL9095986 | 0.66 | CHRNA4 (0.37) | CHRNB2CHRNA4CYP2D6CHRM1CHRM2 | |
| SCHEMBL21095885 | 0.66 | CHRNA7 (0.40) | CHRNB2CHRNA4CYP1A2CYP2D6CHRM1 | |
| SCHEMBL9097794 | 0.65 | CHRNA4 (0.39) | CHRNB2CHRNA4CYP2D6CHRM1CHRM2 | |
| SCHEMBL14559618 | 0.64 | USP2 (0.42) | — | |
| SCHEMBL7278734 | 0.64 | USP2 (0.42) | — | |
| SCHEMBL7278729 | 0.64 | USP2 (0.42) | — | |
| SCHEMBL12663106 | 0.63 | CHRNA4 (0.40) | CHRNB2CHRNA4CYP2D6CHRM1CHRM2 | |
| SCHEMBL14027182 | 0.62 | CHRNA7 (0.42) | CHRNB2CHRNA4CYP2D6CHRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037891-B1 | METHOD FOR PREPARING MEQUITAZINE AND NOVEL SYNTHESIS INTERMEDIATE | PF MEDICAMENT (FR) | 2002-04-10 | — | — | EP | claimed |