Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8184986 | 0.85 | KDM4E (0.41) | MAPTLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8954354 | 0.78 | MAPT (0.45) | MAPTCYP4F2CYP4A11LMNAKDM4E | |
| SCHEMBL8082604 | 0.76 | ALDH1A1 (0.40) | KDM4EALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7532836 | 0.76 | CHRM1 (0.37) | HSD17B10CYP2C19 | |
| SCHEMBL4872569 | 0.76 | HSD17B10 (0.49) | MAPTCYP4F2CYP4A11LMNAKDM4E | |
| SCHEMBL7533293 | 0.75 | CAPN1 (0.41) | SMN1; SMN2 | |
| SCHEMBL7138794 | 0.74 | CYP4F2 (0.46) | MAPTCYP4F2CYP4A11LMNAKDM4E | |
| SCHEMBL15556376 | 0.73 | MAPT (0.52) | MAPTCYP4F2CYP4A11LMNAKDM4E | |
| SCHEMBL8448307 | 0.73 | CYP4F2 (0.45) | MAPTCYP4F2CYP4A11LMNAKDM4E | |
| SCHEMBL21552879 | 0.73 | ALDH1A1 (0.39) | MAPTLMNAKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686149-B1 | USE OF 2-MERCAPTO-IMIDAZOLE DERIVATIVES SUBSTITUTED IN POSITION 4 (OR 5) AS ANTIOXIDIZING AGENTS, METHOD OF PREPARATION AND APPLICATIONS IN THE PHARMACEUTICAL, COSMETIC OR FOOD INDUSTRIES | OXIS ISLE OF MAN LTD (GB) | 2002-04-24 | — | — | EP | claimed |
| US-6056965-A | 2-mercapto-imidazole derivatives substituted in position 4 (or 5) as antioxidizing agents, method of preparation and applications in the pharmaceutical, cosmetic or food industries | OXIS ISLE OF MAN, LIMITED (US) | 2000-05-02 | — | — | US | claimed |
| US-6056965-A | 2-mercapto-imidazole derivatives substituted in position 4 (or 5) as antioxidizing agents, method of preparation and applications in the pharmaceutical, cosmetic or food industries | OXIS ISLE OF MAN, LIMITED (US) | 2000-05-02 | — | — | US | disclosed |