Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539695 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HRH3KDM4ETHRATHRB | |
| SCHEMBL7533296 | 0.76 | MAPT (0.45) | ALDH1A1KDM4EL3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL23861741 | 0.73 | TSHR (0.46) | ALDH1A1HRH3KDM4ETHRATHRB | |
| SCHEMBL21552879 | 0.71 | ALDH1A1 (0.39) | ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL13485578 | 0.67 | TP53 (0.47) | ALDH1A1HRH3KDM4ETHRATHRB | |
| SCHEMBL7532836 | 0.67 | CHRM1 (0.37) | — | |
| SCHEMBL10174987 | 0.67 | ALDH1A1 (0.48) | ALDH1A1HRH3KDM4ETHRATHRB | |
| SCHEMBL822424 | 0.66 | THRB (0.47) | ALDH1A1HRH3KDM4ETHRATHRB | |
| SCHEMBL7533293 | 0.65 | CAPN1 (0.41) | RAB9A | |
| SCHEMBL11027681 | 0.65 | ALDH1A1 (0.47) | ALDH1A1HRH3KDM4ETHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041067-A2 | Use of 2-mercapto-imidazole derivatives substituted in position 4 ( or 5 ) as antioxidants | OXIS Isle of Man, Limited (GB) | 2000-10-04 | — | — | EP | disclosed |