SCHEMBL7533293

SCHEMBL7533293

NC(=O)CCc1c[nH]c(S)n1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 1/20 0.41
MPO P05164 6/20 0.36
NR4A2 P43354 1/20 0.33
SLC6A4 P31645 1/20 0.32
HTT P42858 1/20 0.32
MTNR1A P48039 1/20 0.31
EGFR P00533 1/20 0.31
SRC P12931 1/20 0.31
TP53 P04637 1/20 0.30
RAB9A P51151 1/20 0.30
KLF5 Q13887 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7532836 0.83 CHRM1 (0.37)
Hydrochloric Acid SCHEMBL7422768 0.76 CAPN1 (0.40) CAPN1MPONR4A2SLC6A4HTT
SCHEMBL10714867 0.76
SCHEMBL7534419 0.75 TBXAS1 (0.45)
SCHEMBL7533296 0.75 MAPT (0.45) SMN1; SMN2
SCHEMBL27803112 0.71 XDH (0.36) CAPN1TP53
SCHEMBL4882878 0.71 NR4A2 (0.47) CAPN1MPONR4A2EGFRSRC
SCHEMBL12598559 0.70 MPO (0.38) CAPN1MPOSLC6A4MTNR1A
SCHEMBL1065160 0.70 SLC7A5 (0.45) MPOSLC6A4
SCHEMBL4400036 0.70 QPCT (0.47) MPOHTTMTNR1ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0686149-B1 USE OF 2-MERCAPTO-IMIDAZOLE DERIVATIVES SUBSTITUTED IN POSITION 4 (OR 5) AS ANTIOXIDIZING AGENTS, METHOD OF PREPARATION AND APPLICATIONS IN THE PHARMACEUTICAL, COSMETIC OR FOOD INDUSTRIES OXIS ISLE OF MAN LTD (GB) 2002-04-24 EP claimed
US-6056965-A 2-mercapto-imidazole derivatives substituted in position 4 (or 5) as antioxidizing agents, method of preparation and applications in the pharmaceutical, cosmetic or food industries OXIS ISLE OF MAN, LIMITED (US) 2000-05-02 US claimed
EP-0686149-B1 USE OF 2-MERCAPTO-IMIDAZOLE DERIVATIVES SUBSTITUTED IN POSITION 4 (OR 5) AS ANTIOXIDIZING AGENTS, METHOD OF PREPARATION AND APPLICATIONS IN THE PHARMACEUTICAL, COSMETIC OR FOOD INDUSTRIES OXIS ISLE OF MAN LTD (GB) 2002-04-24 EP disclosed
EP-1041067-A2 Use of 2-mercapto-imidazole derivatives substituted in position 4 ( or 5 ) as antioxidants OXIS Isle of Man, Limited (GB) 2000-10-04 EP disclosed
US-6056965-A 2-mercapto-imidazole derivatives substituted in position 4 (or 5) as antioxidizing agents, method of preparation and applications in the pharmaceutical, cosmetic or food industries OXIS ISLE OF MAN, LIMITED (US) 2000-05-02 US disclosed
EP-0686149-A1 USE OF 2-MERCAPTO-IMIDAZOLE DERIVATIVES SUBSTITUTED IN POSITION 4 (OR 5) AS ANTIOXIDIZING AGENTS, METHOD OF PREPARATION AND APPLICATIONS IN THE PHARMACEUTICAL, COSMETIC OR FOOD INDUSTRIES OXIS INTERNATIONAL S.A. (FR) 1995-12-13 EP disclosed
WO-1995018108-A1 USE OF 2-MERCAPTO-IMIDAZOLE DERIVATIVES SUBSTITUTED IN POSITION 4 (OR 5) AS ANTIOXIDIZING AGENTS, METHOD OF PREPARATION AND APPLICATIONS IN THE PHARMACEUTICAL, COSMETIC OR FOOD INDUSTRIES BIOXYTECH (FR) 1995-07-06 WO disclosed