Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16553896 | 1.00 | GSR (0.53) | GSRDPP7DPP8DPP9MMP2 | |
| SCHEMBL9631019 | 0.98 | GSR (0.55) | GSRDPP7DPP8DPP9MMP2 | |
| SCHEMBL28992842 | 0.98 | GSR (0.55) | GSRDPP7DPP8DPP9MMP2 | |
| SCHEMBL9630987 | 0.93 | GSR (0.47) | GSRDPP7DPP8DPP9MMP2 | |
| Pyrophosphoric Acid SCHEMBL29018593 | 0.88 | DPP7 (0.46) | GSRDPP7DPP8DPP9MMP2 | |
| SCHEMBL2460853 | 0.85 | MDM2 (0.46) | TDP1POLBKMT2AMDM2LMNA | |
| SCHEMBL9344802 | 0.85 | CES2 (0.50) | MMP2TDP1POLBKMT2AMMP9 | |
| SCHEMBL28574985 | 0.85 | CES2 (0.50) | MMP2TDP1POLBKMT2AMMP9 | |
| Hydrochloric Acid SCHEMBL928942 | 0.83 | MMP2 (0.49) | MMP2TDP1POLBKMT2AMMP9 | |
| SCHEMBL29387120 | 0.83 | AKR1C3 (0.46) | GSRDPP7DPP8DPP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002016644-A1 | INHIBITION OF PROTEIN-PROTEIN INTERACTION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-02-28 | — | — | WO | disclosed |